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Antimicrobial resistance (AMR) is a global public health problem. In May 2015, the 68thWorld Health Assembly adopted the Global Action Plan (GAP) on Antimicrobial Resistance. All countries are required to develop their own national action plan based on the GAP, and start implementing it at local level. Accordingly National Action plan for containment of Antimicrobial Resistance in Bangladesh 2017-2022 has been prepared. Surveil-lance of Antimicrobial resistance is an important issue in this plan. Institute of Epidemiology, Disease Control and Research (IEDCR) has been conducting AMR surveillance since 2017 with technical support from US-CDC and WHO to find out the status of Antimicrobial Resistance in Bangladesh. In February 2020, with the suggestion of National technical committee IEDCR is selected as the Sectoral AMR Surveillance Coordination Center for human health and also with the approval of Director General of Health Services, IEDCR has been selected as the National Reference Laboratory for human health for national AMR surveillance. Surveillance activities started in 9 sites all over Bangladesh in 2 phases.